UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                            SCHEDULE 14A INFORMATION
                Proxy Statement Pursuant to Section 14(a) of the
                        Securities Exchange Act of 1934

Filed by the Registrant                         [ X ]
Filed by a Party other than the Registrant      [   ]

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         (as permitted by Rule 14a-6(e)(2))
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[   ]    Soliciting Material under Rule 14a-12


                           OraSure Technologies, Inc.
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                (Name of Registrant as Specified In Its Charter)

- --------------------------------------------------------------------------------
    (Name of Person(s) Filing Proxy Statement, if other than the Registrant)


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[EPITOPE LOGO] September 11, 2000 To: Stockholders of Epitope and STC Technologies Subject: Joint Proxy Statement/Prospectus - OraSure Technologies, Inc. Dear Stockholder: You should have recently received a copy of the joint proxy statement/prospectus for OraSure Technologies, the company that would result from the merger of Epitope and STC Technologies. - -------------------------------------------------------------------------------- THE TOLL-FREE NUMBER LISTED IN THE DOCUMENT HAS AN ERROR AND SHOULD READ: 800-628-8509 - -------------------------------------------------------------------------------- You can call this number if you have questions on material in the proxy statement/prospectus, or if you want to know the number of shares that will be provided to STC Technologies stockholders. The number of shares will not be known with certainty until the 20 trading day period defined in the Agreement and Plan of Merger. This period will end with the close of trading on September 25, 2000. - -------------------------------------------------------------------------------- YOUR VOTE IS IMPORTANT. IF YOU DO NOT EITHER VOTE YOUR SHARES, OR INSTRUCT YOUR STOCKBROKER TO VOTE THEM FOR YOU, IT WILL HAVE THE SAME EFFECT AS VOTING AGAINST THE MERGER. - -------------------------------------------------------------------------------- Sincerely, /s/ Charles E. Bergeron Charles E. Bergeron Chief Financial Officer Epitope Inc.