o
|
Rule
13d-1(b)
|
|
x
|
Rule
13d-1(c)
|
|
o
|
Rule
13d-1(d)
|
CUSIP
No. 68554V108
|
|||||||
1.
|
Names
of Reporting Persons
I.R.S.
Identification Nos. of above persons (entities only)
D.
E. Shaw Valence Portfolios, L.L.C.
13-4046559
|
||||||
2.
|
Check
the Appropriate Box if a Member of a Group (See Instructions)
|
||||||
(a)
|
o
|
||||||
(b)
|
o
|
||||||
3.
|
SEC
Use Only
|
||||||
4.
|
Citizenship
or Place of Organization
Delaware
|
Number
of
Shares
Beneficially
Owned
by
Each
Reporting
Person
With
|
5.
|
Sole
Voting Power
-0-
|
||||
6.
|
Shared
Voting Power
2,569,248
|
|||||
7.
|
Sole
Dispositive Power
-0-
|
|||||
8.
|
Shared
Dispositive Power
2,569,248
|
|||||
9.
|
Aggregate
Amount Beneficially Owned by Each Reporting Person
2,569,248
|
|||||
10.
|
Check
if the Aggregate Amount in Row (9) Excludes Certain Shares (See
Instructions) o
|
|||||
11.
|
Percent
of Class Represented by Amount in Row (9)
5.5%
|
|||||
12.
|
Type
of Reporting Person (See Instructions)
OO
|
CUSIP
No. 68554V108
|
||||||
1.
|
Names
of Reporting Persons
I.R.S.
Identification Nos. of above persons (entities only)
D.
E. Shaw & Co., L.P.
13-3695715
|
|||||
2.
|
Check
the Appropriate Box if a Member of a Group (See Instructions)
|
|||||
(a)
|
o
|
|||||
(b)
|
o
|
|||||
3.
|
SEC
Use Only
|
|||||
4.
|
Citizenship
or Place of Organization
Delaware
|
|||||
Number
of
Shares
Beneficially
Owned
by
Each
Reporting
Person
With
|
5.
|
Sole
Voting Power
-0-
|
||||
6.
|
Shared
Voting Power
2,569,305
|
|||||
7.
|
Sole
Dispositive Power
-0-
|
|||||
8.
|
Shared
Dispositive Power
2,569,305
|
|||||
9.
|
Aggregate
Amount Beneficially Owned by Each Reporting Person
2,569,305
|
|||||
10.
|
Check
if the Aggregate Amount in Row (9) Excludes Certain Shares (See
Instructions) o
|
|||||
11.
|
Percent
of Class Represented by Amount in Row (9)
5.5%
|
|||||
12.
|
Type
of Reporting Person (See Instructions)
IA,
PN
|
CUSIP
No. 68554V108
|
||||||
1.
|
Names
of Reporting Persons
I.R.S.
Identification Nos. of above persons (entities only)
David
E. Shaw
|
|||||
2.
|
Check
the Appropriate Box if a Member of a Group (See Instructions)
|
|||||
(a)
|
o
|
|
||||
(b)
|
o
|
|||||
3.
|
SEC
Use Only
|
|||||
4.
|
Citizenship
or Place of Organization
United
States
|
|||||
Number
of
Shares
Beneficially
Owned
by
Each
Reporting
Person
With
|
5.
|
Sole
Voting Power
-0-
|
||||
6.
|
Shared
Voting Power
2,569,305
|
|||||
7.
|
Sole
Dispositive Power
-0-
|
|||||
8.
|
Shared
Dispositive Power
2,569,305
|
9.
|
Aggregate
Amount Beneficially Owned by Each Reporting Person
2,569,305
|
|||||
10.
|
Check
if the Aggregate Amount in Row (9) Excludes Certain Shares (See
Instructions) o
|
|||||
11.
|
Percent
of Class Represented by Amount in Row (9)
5.5%
|
|||||
12.
|
Type
of Reporting Person (See Instructions)
IN
|
Item
1.
|
||
(a)
|
Name
of Issuer:
|
|
OraSure
Technologies,
Inc.
|
||
(b)
|
Address
of Issuer's Principal Executive Offices:
|
|
220
East First Street
Bethlehem,
Pennsylvania
18015
|
||
Item
2.
|
||
(a)
|
Name
of Person Filing:
|
|
D.
E. Shaw Valence Portfolios, L.L.C.
D.
E. Shaw & Co., L.P.
David
E. Shaw
|
||
(b)
|
Address
of Principal Business Office or, if none, Residence:
|
|
The
business address for each reporting person is:
120
W. 45th
Street, Tower 45, 39th
Floor
New
York, NY 10036
|
||
(c)
|
Citizenship:
|
|
D.
E. Shaw Valence Portfolios, L.L.C. is a limited liability
company
organized under the laws of the state of Delaware.
D.
E. Shaw & Co., L.P. is a limited partnership organized under the
laws
of the state of Delaware.
David
E. Shaw is a citizen of the United States of
America.
|
||
(d)
|
Title
of Class of Securities:
|
|
Common
Stock, $0.000001 par
value
|
||
(e)
|
CUSIP
Number:
|
|
68554V108
|
Item
3.
|
If
this statement is filed pursuant to Rule 13d-1(b) or 13d-2(b) or
(c),
check whether the person filing is a:
|
|||
Not
Applicable
|
Item
4.
|
Ownership
|
|
As
of May 20, 2008:
(a)
Amount beneficially owned:
|
D.
E. Shaw Valence Portfolios, L.L.C.:
|
2,569,248
shares
This
is composed of 2,569,248 shares in
the name of D. E. Shaw Valence
Portfolios, L.L.C.
|
D.
E. Shaw & Co., L.P.:
|
2,569,305
shares
This
is composed of (i) 2,569,248 shares
in the name of D. E. Shaw Valence
Portfolios, L.L.C. and (ii) 57 shares
in the name of D. E. Shaw Synoptic
Portfolios 2,
L.L.C.
|
David
E. Shaw:
|
2,569,305
shares
This
is composed of (i) 2,569,248 shares
in the name of D. E. Shaw Valence
Portfolios, L.L.C. and (ii) 57
shares in the name of D. E. Shaw
Synoptic
Portfolios 2,
L.L.C.
|
D.
E. Shaw Valence Portfolios, L.L.C.:
|
5.5%
|
|
D.
E. Shaw & Co., L.P.:
|
5.5%
|
|
David
E. Shaw:
|
5.5%
|
D.
E. Shaw Valence Portfolios, L.L.C.:
|
-0-
shares
|
|
D.
E. Shaw & Co., L.P.:
|
-0-
shares
|
|
David
E. Shaw:
|
-0-
shares
|
D.
E. Shaw Valence Portfolios, L.L.C.:
|
2,569,248
shares
|
|
D.
E. Shaw & Co., L.P.:
|
2,569,305
shares
|
|
David
E. Shaw:
|
2,569,305
shares
|
D.
E. Shaw Valence Portfolios, L.L.C.:
|
-0-
shares
|
|
D.
E. Shaw & Co., L.P.:
|
-0-
shares
|
|
David
E. Shaw:
|
-0-
shares
|
D.
E. Shaw Valence Portfolios, L.L.C.:
|
2,569,248
shares
|
|
D.
E. Shaw & Co., L.P.:
|
2,569,305
shares
|
|
David
E. Shaw:
|
2,569,305
shares
|
Item
5.
|
Ownership
of Five Percent or Less of a Class
|
|
Not
Applicable
|
||
Item
6.
|
Ownership
of More than Five Percent on Behalf of Another
Person
|
|
Not
Applicable
|
||
Item
7.
|
Identification
and Classification of the Subsidiary Which Acquired the Security
Being
Reported on By the Parent Holding Company or Control Person
|
|
Not
Applicable
|
||
Item
8.
|
Identification
and Classification of Members of the Group
|
|
Not
Applicable
|
||
Item
9.
|
Notice
of Dissolution of Group
|
|
Not
Applicable
|
||
Item
10.
|
Certification
|
|
By
signing below, each of D. E. Shaw Valence Portfolios, L.L.C.,
D. E. Shaw & Co., L.P., and David E. Shaw certify
that, to the best of such reporting person’s knowledge and belief, the
securities referred to above were not acquired and are not
held for the
purpose of or with the effect of changing or influencing
the control of
the issuer of the securities and were not acquired and are
not held in
connection with or as a participant in any transaction having
such
purposes or
effect.
|
|
D.
E. Shaw Valence Portfolios, L.L.C.
|
||
|
By:
|
D.
E. Shaw & Co., L.P., as
managing
member
|
|
|
|
|
|
By: | /s/ Rochelle Elias | ||
|
|
|
Rochelle
Elias
Chief
Compliance Officer
|
D. E. Shaw & Co., L.P. | ||
|
|
|
By: | /s/ Rochelle Elias | |
Rochelle
Elias
Chief
Compliance Officer
|
David E. Shaw | ||
|
|
|
By: | /s/ Rochelle Elias | |
Rochelle
Elias
Attorney-in-Fact
for David E.
Shaw
|
|
D.
E. Shaw Valence Portfolios, L.L.C.
|
||
|
By:
|
D.
E. Shaw & Co., L.P., as
managing
member
|
|
|
|
|
|
By: | /s/ Rochelle Elias | ||
|
|
|
Rochelle
Elias
Chief
Compliance Officer
|
D. E. Shaw & Co., L.P. | ||
|
|
|
By: | /s/ Rochelle Elias | |
Rochelle
Elias
Chief
Compliance Officer
|
David E. Shaw | ||
|
|
|
By: | /s/ Rochelle Elias | |
Rochelle
Elias
Attorney-in-Fact
for David E.
Shaw
|