SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549


                                    FORM 8-K
                                 CURRENT REPORT

                         PURSUANT TO SECTION 13 OR 15(d)
                     OF THE SECURITIES EXCHANGE ACT OF 1934




       Date of Report (Date of earliest event reported): December 15, 2000



                           ORASURE TECHNOLOGIES, INC.
                          ----------------------------
                 (Exact name of issuer as specified in charter)



       DELAWARE                    1-10492                    36-4370966
    (State or Other              (Commission              (I.R.S. Employer
     Jurisdiction                    file                   Identification
  of Incorporation or               number)                    Number)
     Organization)



                               150 Webster Street
                          Bethlehem, Pennsylvania 18015
                    (Address of principal executive offices)


                                 (610) 882-1820
              (Registrant's telephone number, including area code)


Item 5 - Other Events. As is more fully described in the attached press release that is incorporated herein by reference, on December 15, 2000, OraSure Technologies, Inc. announced, among other things, that its next Annual Meeting will take place on June 14, 2001 in Bethlehem, Pennsylvania and that stockholder proposals must be received prior to January 15, 2001 in order to be considered for inclusion in OraSure Technologies' proxy materials for that meeting. Item 7 - Financial Statements, Pro Forma Financial Information and Exhibits. (c) Exhibits Exhibit No. Description 99 OraSure Technologies, Inc. Press Release dated December 15, 2000 1

Signatures Pursuant to the requirements of the Securities and Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned, hereunto duly authorized. ORASURE TECHNOLOGIES, INC. Date: December 15, 2000 By: /s/ Robert D. Thompson ---------------------- Robert D. Thompson Chief Executive Officer 2

Index to Exhibits Exhibit No. Description 99 OraSure Technologies, Inc. Press Release dated December 15, 2000 3


Exhibit 99

[GRAPHIC OMITTED]


Company Contacts:

Michelle Sells              Rich Hooper
Manager, Investor Relations Vice President,
                            Finance
503-641-6115                610-882-1820
Investorinfo@orasure.com
www.orasure.com



                  OraSure Technologies Sets Annual Meeting Date


BEAVERTON,  Ore.  (December 15, 2000) - OraSure  Technologies,  Inc. (Nasdaq NM:
OSUR)  today  announced  that as a result of  changing  from a fiscal  year to a
calendar year ending December 31 for financial reporting  purposes,  the Company
has changed the date set for its next annual meeting of stockholders to June 14,
2001. The meeting will take place in Bethlehem, PA, which is now the location of
the executive offices for OraSure.  A specific meeting site will be communicated
to  stockholders  in the proxy  materials  distributed  for the annual  meeting.
Stockholder  proposals must be received prior to January 15, 2001 in order to be
considered  for  inclusion  in the  Company's  proxy  statement  under  relevant
Securities and Exchange Commission rules and prior to April 25, 2001 in order to
be  considered  at the annual  meeting or to nominate a Director  under  OraSure
Technologies' Bylaws.

About OraSure

OraSure  Technologies,  Inc. develops,  manufactures and markets medical devices
and diagnostic products for use by public- and private-sector clients,  clinical
laboratories, physicians' offices and workplace testing. OraSure Technologies is
the  leading  supplier of oral fluid  collection  devices and assays to the life
insurance  industry and public health markets for the detection of antibodies to
HIV-1.  In addition,  the company  supplies  oral fluid  testing  solutions  for
drugs-of-abuse  testing.  For  more  information  on the  company  please  go to
www.orasure.com.

[PRESS RELEASE]